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Page 1
Did you mean vdr and heart (246 results)?
VEGF-A in Cardiomyocytes and Heart Diseases.
Braile M, Marcella S, Cristinziano L, Galdiero MR, Modestino L, Ferrara AL, Varricchi G, Marone G, Loffredo S. Braile M, et al. Int J Mol Sci. 2020 Jul 26;21(15):5294. doi: 10.3390/ijms21155294. Int J Mol Sci. 2020. PMID: 32722551 Free PMC article. Review.
The relationship between VEGF-A and the heart is double-sided. On the one hand, VEGF-A activates CM, inducing morphogenesis, contractility and wound healing. ...Based on clinical studies on angiogenesis therapy conducted to date, it is possible to think that the control of …
The relationship between VEGF-A and the heart is double-sided. On the one hand, VEGF-A activates CM, inducing morphogenesis, contract …
Monocyte-derived and CD34+/KDR+ endothelial progenitor cells in heart failure.
Shantsila E, Wrigley BJ, Shantsila A, Tapp LD, Gill PS, Lip GY. Shantsila E, et al. J Thromb Haemost. 2012 Jul;10(7):1252-61. doi: 10.1111/j.1538-7836.2012.04753.x. J Thromb Haemost. 2012. PMID: 22519984 Free article.
BACKGROUND: Endothelial progenitor cells (EPCs) are known to be altered in heart failure (HF), but monocyte-derived EPCs in HF have not been assessed. ...We also enumerated CD34(+)/KDR(+) EPCs derived from mononuclear cells ('classic' EPC definition). ...
BACKGROUND: Endothelial progenitor cells (EPCs) are known to be altered in heart failure (HF), but monocyte-derived EPCs in HF have n …
The guidance receptor plexin D1 is a mechanosensor in endothelial cells.
Mehta V, Pang KL, Rozbesky D, Nather K, Keen A, Lachowski D, Kong Y, Karia D, Ameismeier M, Huang J, Fang Y, Del Rio Hernandez A, Reader JS, Jones EY, Tzima E. Mehta V, et al. Nature. 2020 Feb;578(7794):290-295. doi: 10.1038/s41586-020-1979-4. Epub 2020 Feb 5. Nature. 2020. PMID: 32025034 Free PMC article.
Defining the clinical validity of genes reported to cause pulmonary arterial hypertension.
Welch CL, Aldred MA, Balachandar S, Dooijes D, Eichstaedt CA, Gräf S, Houweling AC, Machado RD, Pandya D, Prapa M, Shaukat M, Southgate L, Tenorio-Castano J; ClinGen PH VCEP; Chung WK; International Consortium for Genetic Studies in Pulmonary Arterial Hypertension (PAH-ICON) at the Pulmonary Vascular Research Institute (PVRI). Welch CL, et al. Genet Med. 2023 Nov;25(11):100925. doi: 10.1016/j.gim.2023.100925. Epub 2023 Jul 5. Genet Med. 2023. PMID: 37422716
Genetic testing is currently recommended for adults diagnosed with heritable, idiopathic, anorexigen-, hereditary hemorrhagic telangiectasia-, and congenital heart disease-associated PAH, PAH with overt features of venous/capillary involvement, and all children diagnosed w …
Genetic testing is currently recommended for adults diagnosed with heritable, idiopathic, anorexigen-, hereditary hemorrhagic telangiectasia …
Discontinuation versus continuation of renin-angiotensin-system inhibitors in COVID-19 (ACEI-COVID): a prospective, parallel group, randomised, controlled, open-label trial.
Bauer A, Schreinlechner M, Sappler N, Dolejsi T, Tilg H, Aulinger BA, Weiss G, Bellmann-Weiler R, Adolf C, Wolf D, Pirklbauer M, Graziadei I, Gänzer H, von Bary C, May AE, Wöll E, von Scheidt W, Rassaf T, Duerschmied D, Brenner C, Kääb S, Metzler B, Joannidis M, Kain HU, Kaiser N, Schwinger R, Witzenbichler B, Alber H, Straube F, Hartmann N, Achenbach S, von Bergwelt-Baildon M, von Stülpnagel L, Schoenherr S, Forer L, Embacher-Aichhorn S, Mansmann U, Rizas KD, Massberg S; ACEI-COVID investigators. Bauer A, et al. Lancet Respir Med. 2021 Aug;9(8):863-872. doi: 10.1016/S2213-2600(21)00214-9. Epub 2021 Jun 11. Lancet Respir Med. 2021. PMID: 34126053 Free PMC article. Clinical Trial.
Vasculogenesis and angiogenesis.
Patan S. Patan S. Cancer Treat Res. 2004;117:3-32. doi: 10.1007/978-1-4419-8871-3_1. Cancer Treat Res. 2004. PMID: 15015550 Review.
Two distinct mechanisms, vasculogenesis and angiogenesis implement the formation of the vascular network in the embryo. Vasculogenesis gives rise to the heart and the first primitive vascular plexus inside the embryo and in its surrounding membranes, as the yolk sac circul …
Two distinct mechanisms, vasculogenesis and angiogenesis implement the formation of the vascular network in the embryo. Vasculogenesis gives …
CaMKII inhibitor KN-93 impaired angiogenesis and aggravated cardiac remodelling and heart failure via inhibiting NOX2/mtROS/p-VEGFR2 and STAT3 pathways.
Ni Y, Deng J, Bai H, Liu C, Liu X, Wang X. Ni Y, et al. J Cell Mol Med. 2022 Jan;26(2):312-325. doi: 10.1111/jcmm.17081. Epub 2021 Nov 29. J Cell Mol Med. 2022. PMID: 34845819 Free PMC article.
Persistent cardiac Ca(2+) /calmodulin-dependent Kinase II (CaMKII) activation was considered to promote heart failure (HF) development, some studies believed that CaMKII was a target for therapy of HF. ...We concluded that KN-93 impaired angiogenesis and aggravated cardiac …
Persistent cardiac Ca(2+) /calmodulin-dependent Kinase II (CaMKII) activation was considered to promote heart failure (HF) developmen …
Neovascularization in the human heart is associated with expression of VEGF-A and its receptors Flt-1 (VEGFR-1) and KDR (VEGFR-2). Results from cardiomyopexy in ischemic cardiomyopathy.
Waltenberger J, Kranz A, Beyer M. Waltenberger J, et al. Angiogenesis. 1999;3(4):345-51. doi: 10.1023/a:1026585900398. Angiogenesis. 1999. PMID: 14517414
Cardiomyopexy is a novel means of revascularization in end-stage ischemic heart disease leading to neovascularization and increased perfusion of the damaged heart. ...The spatial expression pattern of VEGF-A and KDR suggests VEGF-A to be a promotor of angioge …
Cardiomyopexy is a novel means of revascularization in end-stage ischemic heart disease leading to neovascularization and increased p …
The patterns and expression of KDR in normal tissues of human internal organs.
Huang J, Zhu H, Wang X, Tang Q, Huang H, Wu K, Zhu J, Feng Z, Shi G. Huang J, et al. J Mol Histol. 2011 Dec;42(6):597-603. doi: 10.1007/s10735-011-9355-1. Epub 2011 Sep 10. J Mol Histol. 2011. PMID: 21909756
The expression of KDR mRNA and protein in perinatal internal organs were all higher than in adult organs including brain, kidney, liver, lung and heart, respectively. ...Notably, the order of KDR protein expression from highest to lowest is as follows: brain, …
The expression of KDR mRNA and protein in perinatal internal organs were all higher than in adult organs including brain, kidney, liv …
412 results